Thursday, 18 August 2016

Acute Myocarditis in a Patient Using Testosterone Diagnosed by Cardiac MR

A 39-year-old male with past medical history of hypothyroidism, hyperlipidemia and asthma presented to our emergency room with sub-sternal crushing type of chest pain. The pain was ongoing for the past hour, present at rest, 8/10 in intensity, non-radiating and was not relieved by sublingual nitroglycerine. Two days prior to presentation, the patient had flu like symptoms with low-grade fever, myalgia, sore throat and nasal congestion. He was a non-smoker and denied any illicit drug abuse. The patient had no significant family history. The patient’s home medications included inhaled fluticasone-salmeterol, simvastatin, levothyroxine and testosterone injection 200 mg IM once every 2 weeks, which he had been taking for 6 months.

Acute Myocarditis in a Patient
In the emergency room, he was afebrile and his vital signs were stable. Cardiovascular and respiratory examination was normal. His initial EKG showed 1 mm ST elevations in lead I and aVL with reciprocal ST depressions in lead III and aVF (Figure 1). His initial troponin was 2.08, which later peaked to 40, and his initial CKMB value was 26.6, which later peaked to 77.6. His chest radiograph was normal.


Patient was initially given aspirin 325 mg, clopidogrel 300 mg and was started on IV heparin drip at 1000 units/hour after a bolus of 5000 units. Subsequently, the patient underwent coronary catheterization, which showed normal coronaries with no occlusion. A transthoracic echocardiogram showed 50-55% ejection fraction with mild hypokinesis of the mid anteroseptal wall.

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