Oral lichen planus (OLP) is a chronic
inflammatory disease characterized by cellular-mediated inflammatory reactions
which render apoptotic epithelial cells and degeneration of the basal
epithelial layer. Eighteen volunteering cases of OLP were scheduled, after
getting their informed consents, to be reported in this study. All of them were
diagnosed histologically.
The diagnosis was confirmed via
immunofluorescence. Another incisional sample was scheduled
after finishing the recruited treatment. The patient histological findings
were contrasted, before and after treatment, to ten cases of non-lesional
archival cases of oral mucosa as a control group.
Results revealed no difference in the response
to the pharmaceutical form of steroids used in treating OLP. Although steroid
therapy is the mainstay treatment of OLP, adjuvant treatment modalities should
be recruited for improving the healing process.
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