Insulin
resistance is characteristic of patients with metabolic syndrome and it’s more
pronounced in overweight patients. In the long term there may be cardiovascular
and pressor consequences. Lifestyle and diet changes may
partly improve these aspects.
The use of
insulin-sensitizing drugs such as metformin gives good results, although side
effects limit its use. Recently, new molecules exerting a similar effect
without side effects have been put on the market, such as the d-chiro-inositol,
a new insulin-sensitizing molecule. Have been proposed various associations
between inositol and ingredients able to potentiate its therapeutic effect.
This was a
prospective study. 40 women were recruited aged >40 years in perimenopause
with metabolic syndrome with insulin resistance, altered lipid parameters and
with a BMI>25.
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