Despite rising
incidence of diabetes in India, we currently lack country wide data on the
prevalence of CKD in T2DM patients. Hence this nationwide study was planned.
Methods: This was a nationwide, cross-sectional, observational, multi-centric
study to assess prevalence of CKD among T2DM patients. The primary
endpoint of the study was to estimate proportion of T2DM patients with CKD
(glomerular filtration rate [GFR] <60 ml/min/1.73 m2or albumin creatinine
ratio [ACR] ≥ 30 mg/g or ≥ 3 mg/mmol or both).
The blood/plasma
and urine samples, were collected for estimation of hemoglobin A1c,
microalbuminuria, serum creatinine, urine creatinine, and routine urine
analysis. Results: Of the 3043 screened subjects, 3000 eligible subjects were
enrolled, out of which 46% were females. The mean age was 53.4 (± 11.9) years,
with a mean body mass index of 27.3 (± 4.8) kg/m2.
Both micro and
macro vascular complications were reported. In the studied population with
T2DM, 47.8% had mildly decreased, 15.1% had mild to moderately decreased, and
1.8% had severely decreased GFR respectively. As per ACR categorization, 61.3%
had normal to mildly increased ACR, 25.6% with moderately increased and 7.2%
with severely increased ACR were seen.
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