Tuesday 20 June 2017

Body Weight Reduction and QTc Interval in Obesity

Body Weight Reduction
Obesity is associated with wide variety of electrocardiographic (ECG) abnormalities. Prolonged QTc interval is common in obesity and it represents a delayed ventricular repolarisation which is associated with ventricular arrhythmias, syncope and sudden cardiac death.

The aim of our study is to evaluate the effects of weight reduction on QTc interval in obese subjects. The study included 74 obese subjects aged 41.78 ± 10.70 years, treated with a lowcalorie diet (800 kcal/day) for two weeks.

All patients underwent a standard resting 12-lead surface ECG before and after the treatment. QTc intervals were corrected by Bazett’s formula. Results: The average loss in body weight was 10.26 ± 3.63%, and the average reduction in body mass index was 9.39 ± 4.23%.

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