Potential Benefit of Postprandial Exercise for Those with Type 1 Diabetes

Currently, less than one-third of individuals with type 1 diabetes are considered to be in good glycemic control with an A1C <7%, increasing the risk of short- and long-term complications.

Considering the annual cost of type 1 diabetes care to the individual, estimated to be $6,288 per year in a 2010 paper and the increasing price of insulin, effective and realistic low/no cost strategies to improve glycemic control are needed not only to reduce the expense to the individual with type 1 diabetes.

But also to prevent the short and long term complications of poor glycemic control and minimize the negative consequences of high insulin dosages, such as possible weight gain.

PDF LINK

In Vivo Antidiabetic Effect of Aqueous Leaf Extract of Azardirachta indica, A. juss in Alloxan Induced Diabetic Mice

There is growing interest in the potential of plant remedies to treat and manage many diseases owing to the adverse side effects, unavailability and unaffordability associated with the conventional therapy.

Among the traditional plants that has been prescribed for clinical use for many ailments including diabetes mellitus is Azardirachta indica. Their continued use is largely based on their long-term therapeutic effects although this has not been authenticated scientifically.

This study therefore, aims to evaluate the in vivo hypoglycemic effect of aqueous leaf extracts of A. indica in alloxan-induced white male albino mice.

PDF LINK

A Case of Back Abscess and Diabetic Ketoacidosis in a Patient with Type 2 Diabetes Mellitus

Patients with type 2 diabetes mellitus (DM) who have poor glycemic control are susceptible to severe bacterial infections and complications such as diabetic ketoacidosis (DKA), which may in turn further exacerbate the bacterial infection.

Commonly reported bacterial infections in DM patients in Japan have included infections of the respiratory system, kidney and urinary tract, and skin and soft tissue.

Deresinski reported that DKA is precipitated or complicated by infections in 75% of the cases. The author also reported that the mortality rate of patients with DKA and infections is 43%.

PDF LINK

The Relationship between Zinc and Insulin Signaling: Implications for Type 2 Diabetes

Type 2 diabetes (T2D) is a debilitating metabolic disorder that is typically characterized by chronic hyperglycaemia and is concomitant with a range of other complications including cardiovascular disease, stroke, peripheral neuropathy, and renal disease.

The aetiology of T2D is highly complex and reflects multifaceted interactions with genetics and the environment, and thus requires a multipronged approach to develop better management and treatments options that are more patient tolerable.

These are urgently needed to reduce the clinical symptoms and features of the disease.

PDF LINK