There are great
concerns regarding the use of synthetic progesterone during breastfeeding due
to probable negative effects on future fecundity of male infants. Therefore the
present study was conducted to evaluate the effects of exposing male rat pups
to depot medroxyprogesterone
acetate (DMPA) during lactational period on pubertal testicular histology,
morphometry and cells quantitation.
Twenty male
Wistar rat pups reared to dams treated with DMPA (10 mg/ kg BW) every other day
during their early lactation period; were employed to achieve the objectives of
this study.
Other 20 male rat
pups reared to untreated dams served as control. The pups were allowed to reach
90 days old, sacrificed, their testes were dissected and weighed and
histological sections were prepared.
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