S1PR2 is one of
five known sphingosine-1-phosphate receptors and has recently been discussed to
be implicated in the development or progression of diabetes.
Our aim was to
identify S1PR2 polymorphisms in the coding region of the human S1PR2 gene
and perform association analyses between S1PR2 polymorphisms leading to amino
acid exchanges and phenotypic parameters in a clinical study cohort.
Method: We
screened the coding region of the S1PR2 gene for polymorphisms resulting in
amino acid exchanges in the S1PR2 protein in 40 Caucasian DNA samples from a
CEPH control panel.
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