Break the Resistance to Fuel Metabolism: A Long Journey with Bright Future

Metabolic syndrome is characterized by systemic insulin resistance that impairs the ability of insulin to regulate fuel (such as glucose and fat) metabolism.

This syndrome has become a global epidemic problem with estimates of prevalence ranging from 20 to 40% in different populations and has been recognized as a powerful risk factor for the development of cardiovascular disease and type 2 diabetes.

Thus, effectively fighting this disastrous health problem is a matter of utmost urgency.

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Association of Vitamin D Level and Subclinical Coronary Artery Disease

The role of vitamin D level in subclinical atherosclerosis remains controversial. We aimed to investigate the relationship between vitamin D level and coronary artery calcium score (CACS).

We investigated 303 consecutive patients referred to an outpatient clinic for CACS. The 25-hydroxy vitamin D [25(OH) D] levels were checked within three months of CACS evaluation. Vitamin D levels of <30 and <20 ng/mL were used as thresholds of vitamin D insufficiency and deficiency, respectively.

The correlation between CACS and vitamin D was assessed. Unadjusted and covariate-adjusted logistic regression analyses were used to predict positive CACS.

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